L-cysteine sulfinic acid
metaboliteL-cysteine sulfinic acid reflects systemic oxidative stress and amino acid metabolism alterations in acute MI.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencemedium
RationaleCysteine oxidation metabolite; systemic redox and metabolic status marker independent of atherothrombotic cascade.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum, plasma or urine
Collection tube
Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container
Method / principle
LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available
Reagent / substrate
Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent
Platform
LC-MS/MS; some automated chemistry
Turnaround · availability
Send-out / research · Specialized / research
Literature evidence(1)
- High-resolution metabolomics study revealing l-homocysteine sulfinic acid, cysteic acid, and carnitine as novel biomarkers for high acute myocardial infarction risk.Metabolism: clinical and experimental · 2019 · PMID 31874143 · doi