Lysophosphatidylethanolamine (16:1)
lipidDecreased lysophosphatidylethanolamine content predicts heart-failure development after acute myocardial infarction.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencemedium
RationaleLipid remodeling marker; post-MI cardiac dysfunction predictor.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma (EDTA to limit oxidation)
Collection tube
K2/K3-EDTA (lavender-top) · Serum separator (gold/red-top, SST)
Method / principle
LC-MS/MS lipidomics (targeted or shotgun)
Reagent / substrate
Deuterated lipid-class internal standards; MS/MS transitions
Platform
LC-MS/MS
Turnaround · availability
Research · Research-only
Literature evidence(1)
- Lipidomic analyses reveal potential biomarkers for predicting death and heart failure after acute myocardial infarction.Clinica chimica acta; international journal of clinical chemistry · 2024 · PMID 39068962 · doi