Lysophosphatidylethanolamines
lipidElevated lysophosphatidylethanolamines reflect lipid remodeling and oxidative stress in atherosclerotic plaque.
Pathway placement
Cascade stepLipid retention & oxidation
Confidencemedium
RationaleAltered lipidome biomarker; phospholipid oxidation/remodeling product.
Also acts inVascular inflammation
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma (EDTA to limit oxidation)
Collection tube
K2/K3-EDTA (lavender-top) · Serum separator (gold/red-top, SST)
Method / principle
LC-MS/MS lipidomics (targeted or shotgun)
Reagent / substrate
Deuterated lipid-class internal standards; MS/MS transitions
Platform
LC-MS/MS
Turnaround · availability
Research · Research-only
Literature evidence(1)
- Human serum lipidomics analysis revealed glyphosate may lead to lipid metabolism disorders and health risks.Environment international · 2022 · PMID 36495677 · doi