microRNA-26a
rnaMicroRNA-26a regulates pathological angiogenesis in myocardial repair but is off-pathway to atherothrombotic occlusion.
Pathway placement
Cascade stepOff-pathway / systemic markers
Confidencelow
RationaleRegulates angiogenesis in reperfused myocardium; post-MI healing marker, not cascade-specific.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)
Literature evidence(1)
- MicroRNA-26a regulates pathological and physiological angiogenesis by targeting BMP/SMAD1 signaling.Circulation research · 2013 · PMID 24047927 · doi