miR-130a-3p

rna

miR-130a-3p dysregulation impairs endothelial function and promotes vascular inflammation in coronary artery disease pathogenesis.

Pathway placement

Cascade stepPlaque inflammation

Confidencemedium

RationaleEndothelial dysfunction and vascular inflammation in coronary disease.

Also acts inEndothelial activation/erosion

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Whole blood or cell-free plasma

Collection tube

PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)

Method / principle

RT-qPCR (TaqMan) or small-RNA sequencing

Reagent / substrate

Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)

Platform

qPCR instrument / NGS

Turnaround · availability

Research / send-out · Research (few LDTs)