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miR-133b
Pathway / Myocardial injury (shared endpoint)

miR-133b

rna

A circulating microRNA downregulated in coronary artery disease that regulates myogenic differentiation and inflammatory responses in ischemic tissue.

Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencemedium
RationalemiRNA downregulated early in CAD; muscle differentiation and inflammation regulator.
Also acts inVascular inflammation
Druggability
Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)

Literature evidence(1)