miR-182-5p
rnamiR-182-5p differentially circulates in acute coronary syndromes, enabling classification of ACS subtypes and MI detection.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencemedium
RationaleACS subtype discrimination; circulates during acute myocardial injury.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)
Literature evidence(1)
- Discriminatory power of a circulating multi-noncoding RNA panel in acute coronary syndrome subtypes: Towards precision detection.The international journal of biochemistry & cell biology · 2024 · PMID 38280541 · doi