miR-186

rna

miR-186 dysregulation after MI associates with adverse myocardial remodeling and long-term mortality risk.

Pathway placement

Cascade stepMyocardial injury (shared endpoint)

Confidencemedium

RationalePredicts long-term mortality post-MI; likely reflects myocardial remodeling and injury burden.

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Whole blood or cell-free plasma

Collection tube

PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)

Method / principle

RT-qPCR (TaqMan) or small-RNA sequencing

Reagent / substrate

Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)

Platform

qPCR instrument / NGS

Turnaround · availability

Research / send-out · Research (few LDTs)