miR-203
rnamiR-203 is an early circulating biomarker for STEMI onset, marking acute myocardial necrosis ahead of troponin rise.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencehigh
RationaleEarly STEMI prediction biomarker; upregulated in acute myocardial necrosis.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)
Literature evidence(1)
- Serum miRNA-203 as a Novel Biomarker for the Early Prediction of Acute ST-elevation Myocardial Infarction.Journal of cardiovascular translational research · 2022 · PMID 35507256 · doi