miR-210-3p
rnamiR-210-3p is upregulated in response to myocardial ischemia and hypoxia, differentiating MI from other acute cardiac presentations.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencehigh
RationaleHypoxia-responsive microRNA; cardiomyocyte ischemia and early-injury marker discriminating MI.
Also acts inVascular inflammation
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)
Literature evidence(1)
- Alteration of circulating miRNAs during myocardial infarction and association with lipid levels.Laboratory medicine · 2024 · PMID 38048807 · doi