miR-96-5p
rnamiR-96-5p is elevated in acute myocardial infarction and regulates cardiomyocyte apoptosis through suppression of anti-apoptotic BCL2L13.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencemedium
RationaleCardiomyocyte injury marker; targets BCL2L13 in cell death pathways.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Whole blood or cell-free plasma
Collection tube
PAXgene/Tempus RNA tube · K2/K3-EDTA (lavender-top)
Method / principle
RT-qPCR (TaqMan) or small-RNA sequencing
Reagent / substrate
Target-specific primers/probe; reverse transcriptase (miRNA: stem-loop RT primer)
Platform
qPCR instrument / NGS
Turnaround · availability
Research / send-out · Research (few LDTs)
Literature evidence(1)
- Serum miR-96-5p is a novel and non-invasive marker of acute myocardial infarction associated with coronary artery disease.Bioengineered · 2022 · PMID 35109756 · doi