Monomeric C-reactive protein
proteinmCRP drives plaque inflammation and is elevated in acute MI, reflecting inflammatory activation.
Pathway placement
Cascade stepPlaque inflammation
Confidencemedium
RationaleCRP component with plaque-inflammatory role; acute-phase marker of plaque destabilization in MI.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Increased monomeric CRP levels in acute myocardial infarction: a possible new and specific biomarker for diagnosis and severity assessment of disease.Atherosclerosis · 2015 · PMID 25682033 · doi