MR-PAMP
proteinMR-PAMP is a myocyte-derived danger signal released during cardiomyocyte necrosis in acute myocardial infarction.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencehigh
RationaleMyocyte-derived damage-associated molecular pattern released on cardiomyocyte necrosis.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Beyond the Limits: Clinical Utility of Novel Cardiac Biomarkers.BioMed research international · 2015 · PMID 26504786 · doi