Myeloperoxidase-oxidized LDL

lipoprotein

Myeloperoxidase-oxidized LDL is an inflammatory lipoprotein modification that promotes foam cell differentiation and endothelial dysfunction.

Pathway placement

Cascade stepPlaque inflammation

Confidencehigh

RationaleMPO-catalyzed LDL modification; drives foam cell formation and endothelial dysfunction.

Also acts inLipid entry/oxidation

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Specialized reference method

Specimen

Serum or plasma (EDTA)

Collection tube

K2/K3-EDTA (lavender-top) · Serum separator (gold/red-top, SST)

Method / principle

Sandwich ELISA against the modified-apoB neoepitope

Reagent / substrate

Anti-modified-LDL monoclonal capture + anti-apoB detection

Platform

ELISA plate

Turnaround · availability

Research · Research/CE