N-lactoyl-phenylalanine
metaboliteN-lactoyl-phenylalanine is a metabolite of mitochondrial dysfunction and inflammation associated with acute myocardial infarction risk.
Pathway placement
Cascade stepPlaque inflammation
Confidencelow
RationaleMitochondrial metabolite linked to diabetes and AMI pathophysiology.
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum, plasma or urine
Collection tube
Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container
Method / principle
LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available
Reagent / substrate
Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent
Platform
LC-MS/MS; some automated chemistry
Turnaround · availability
Send-out / research · Specialized / research
Literature evidence(1)
- Precise Metabolomics Defines Systemic Metabolic Dysregulation Distinct to Acute Myocardial Infarction Associated With Diabetes.Arteriosclerosis, thrombosis, and vascular biology · 2023 · PMID 36727520 · doi