Pentadecanoic acid (C15:0)
metaboliteIschemia-reperfusion injury triggers fatty acid mobilization and mitochondrial lipid catabolism.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencemedium
RationaleOdd-chain fatty acid released during ischemic lipid remodeling and cardiomyocyte injury.
Also acts inLipid entry/oxidation
Druggability
Not assessed (no mapped human gene target).
Type I vs Type II discrimination
ScoresLow-confidence (proxy)
R — rupture / Type-I20
C — confounder / Type-II42
A — assay feasibility42
E — evidence strength16
T1DI (composite)3
Specificity differential (R−C)-21.7
Confounder panel (Type-II drivers)
No confounder evidence retrieved.
Tier: light (literature co-occurrence proxy — lower confidence). See the discrimination table for all markers.
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum, plasma or urine
Collection tube
Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container
Method / principle
LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available
Reagent / substrate
Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent
Platform
LC-MS/MS; some automated chemistry
Turnaround · availability
Send-out / research · Specialized / research
Literature evidence(1)
- Metabolomic characterization of myocardial ischemia-reperfusion injury in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention.Scientific reports · 2019 · PMID 31409856 · doi