Taurine
metaboliteTaurine is a conditionally essential amino acid that provides cardioprotection during myocardial ischemia-reperfusion and supports long-term post-MI recovery.
Pathway placement
Cascade stepMyocardial injury (shared endpoint)
Confidencemedium
RationaleCardioprotective amino acid; regulates myocardial ischemia-reperfusion and metabolic recovery.
Also acts inSystemic / off-pathway
Druggability
Not assessed (no mapped human gene target).
Type I vs Type II discrimination
ScoresLow-confidence (proxy)
R — rupture / Type-I56
C — confounder / Type-II93
A — assay feasibility42
E — evidence strength34
T1DI (composite)5
Specificity differential (R−C)-36.3
Confounder panel (Type-II drivers)
No confounder evidence retrieved.
Tier: light (literature co-occurrence proxy — lower confidence). See the discrimination table for all markers.
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum, plasma or urine
Collection tube
Serum separator (gold/red-top, SST) · Lithium heparin (green-top) · Sterile urine container
Method / principle
LC-MS/MS (targeted metabolomics) or enzymatic colorimetric where available
Reagent / substrate
Stable-isotope-labeled internal standard (MS); or enzyme-coupled Trinder reagent
Platform
LC-MS/MS; some automated chemistry
Turnaround · availability
Send-out / research · Specialized / research
Literature evidence(4)
- LC-MS-based metabolomics reveals metabolic changes in short- and long-term administration of Compound Danshen Dripping Pills against acute myocardial infarction in rats.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2022 · PMID 35717805 · doi
- Modified Taohong Siwu decoction improves cardiac function after myocardial ischaemia and reperfusion in rats by promoting endogenous stem cell mobilization and regulating metabolites.Pharmaceutical biology · 2022 · PMID 36086864 · doi
- Metabolomic analysis of serum and myocardium in compensated heart failure after myocardial infarction.Life sciences · 2019 · PMID 30731143 · doi
- Alterations in the gut microbiome and metabolism with coronary artery disease severity.Microbiome · 2019 · PMID 31027508 · doi