Urotensin II Receptor
proteinUrotensin II receptor transduces vasoconstrictor and pro-inflammatory signals during atherosclerotic plaque evolution.
Pathway placement
Cascade stepEndothelial activation & erosion
Confidencemedium
RationaleMediates U-II vasoconstriction and atherosclerotic signaling pathway.
Also acts inVascular inflammation
Druggability
Not assessed (no mapped human gene target).
Assay & specimen
Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.
Specimen
Serum or plasma
Collection tube
Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)
Method / principle
Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists
Reagent / substrate
Matched anti-target antibody pair (capture + labeled detection)
Platform
ELISA microplate or multiplex (Luminex/MSD)
Turnaround · availability
Send-out / research · Research-grade (no universal clinical assay)
Literature evidence(1)
- Role of urotensin II in atherosclerotic cardiovascular diseases.Cardiovascular revascularization medicine : including molecular interventions · 2008 · PMID 18606380 · doi