Cardiac Troponin T/I

TNNT2/TNNI3protein

Cardiac troponins released from injured cardiomyocytes are the diagnostic standard for myocardial infarction detection and risk stratification.

Pathway placement

Cascade stepMyocardial injury (shared endpoint)

Confidencehigh

RationaleAnchor for myocardial injury endpoint; gold-standard MI diagnostic marker.

Druggability

Not assessed (no mapped human gene target).

Assay & specimen

Class-level default (no specific cleared assay)— generic method inferred from analyte class; confirm against a specific product insert before use.

Specimen

Serum or plasma

Collection tube

Serum separator (gold/red-top, SST) · K2/K3-EDTA (lavender-top)

Method / principle

Sandwich immunoassay (ELISA) — research-grade unless a cleared assay exists

Reagent / substrate

Matched anti-target antibody pair (capture + labeled detection)

Platform

ELISA microplate or multiplex (Luminex/MSD)

Turnaround · availability

Send-out / research · Research-grade (no universal clinical assay)